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Since APAP is responsible for nearly half of the cases of acute liver failure in the United States and remains the leading cause for liver transplantation, continued awareness, education and research should be undertaken

However, other systems downstream of cystine uptake can also play an important role

While originally studied for its effect on the pineal gland, researchers have experimented with its overall well-being

Different parameters were used to evaluate the treatment results, such as vibration perception threshold, neurological symptom and disability scores, and visual analogue scale (VAS) for pain, and patients treated with ALA achieved significantly better results than the placebo group