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doi: 10.3892/etm.2019.8388 316 LiGMaXDengLZhaoXWeiYGaoZet al

10.1007/s12035-014-8705-x 76 MoyseE.KranticS.DjellouliN.RogerS.AngoulvantD.DebacqC.et al (2022)

Although ibuprofen works well at relieving pain, using it long term could possibly result in a person becoming dependent on pain relievers since ibuprofen may be inducing sEH activity which causes an underlying pain in that person

The amount of BA ingested that is converted into muscle carnosine is only about 36% (47), while small amounts (~3%) are also lost via the urine ( It appears reasonable to expect that any changes in muscle carnosine content would be paralleled by changes in the proteins involved in its metabolism