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On the other hand, 22 metabolic pathways were significantly downregulated in GDH3 -deleted cells cultured in MM medium and only oxidative phosphorylation, sulphur metabolism, biotin metabolism, pyrimidine metabolism, and glycolysis/gluconeogenesis were upregulated

The elevated antioxidant capacity driven by persistent NRF2 activation and enhanced glutathione (GSH) and thioredoxin (TRX) systems enables cancer cells to withstand endogenous oxidative stress and promotes metastatic behavior

Pierson R, Corson PW, Sears LL, Alicata D, Magnotta V, Oleary D et al (2002)

It utilizes a combination of glycolic acid and salicylic acid to gently loosen the pores