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High cost and insurance restrictions are common, with many plans requiring step therapy, higher BMI, or documented inability to lose weight by other methods before approval. Do GLP-1 drugs replace the need for arthritis or autoimmune medications

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We have a lead compound that we really want to explore, because it does, in fact, interact with a viral protein in the way that we predicted it to interact, so it has a chance of inhibiting viral entry into a host cell, says Brad Pentelute, an MIT associate professor of chemistry, who is leading the research team