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Lopez BL et al

The Los Angeles Times (11/1, Morin) reports that a study in mice suggests that those among us with ginger hair and fair complexions face an elevated risk of skin cancer even when covered up. The research, published online Wednesday in the journal Nature, suggests that the same reddish-yellow pigment that gives rise to rusty locks and an inability to tan is itself a potential trigger in the development of melanoma, the deadliest form of skin cancer. HealthDay (11/1, Dotinga) reports that researchers tinkered with the genetic makeup of mice, giving them a mutant form of a gene that boosts the risk of melanoma

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In addition, energy stores (ATP) become depleted, whereas the expression of proinflammatory cytokines, adhesion molecules, and bioactive agents such as endothelin and thromboxane A 2 become accelerated [59,60]