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Per capita alcohol consumption increased significantly between 1950 and 1970, and tobacco consumption increased between 1950 and 1966 and decreased steadily after that

Call your doctor or dentist if you have: Unusually large sores Sores that spread Sores that last 2 weeks or longer Extreme pain despite avoiding trigger foods and taking over-the-counter pain medication Trouble drinking enough fluids A high fever with canker sores Frequent or lasting mouth sores, which may be a sign of problems such as a serious skin disorder called pemphigus, celiac disease, inflammatory bowel disease, Behcet's disease, an autoimmune disease, anemia, or HIV

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