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I'm not medically trained just someone who suffered for years from unrecognised and untreated B12 deficiency

[17] [22] Patients with pre-existing cardiovascular disease should use ibuprofen cautiously and discuss appropriate pain management strategies with their healthcare provider

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People who have had intestinal surgery, such as weight loss surgery, or who have digestive disorders, such as celiac disease or Crohns disease, which may reduce the amount of vitamin B12 the body can absorb