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We observed that there was a statistically significant difference between the group means F(2,6) = 380.59, p = 4.78E 07 , F critical value = 5.14 (Fig

reported strong expression of HIF-1 in the intimal layer of macrophage-like synoviocytes (MLS) in human RA synovium (128), while HIF-2 is mainly expressed in fibroblast-like synoviocytes (FLS) in human RA synovium and collagen-induced arthritis model (CIA) (129)

doi: 10.1017/S0007114510000176 58 SchwiertzA.TarasD.SchferK.BeijerS.BosN

Comparison to Semaglutide: Whereas Semaglutide primarily targets glucose regulation and satiety, Retatrutide expands into energy metabolism and lipid turnover