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4 BahramiA.ShahidsalesS.KhazaeiM.Ghayour-MobarhanM.MaftouhM.HassanianS

Nat Rev Mol Cell Biol 25(1):4664

In probing the pathway of celiac disease, researchers wondered if the seemingly minor modification of the gluten-derived peptides by tissue transglutaminase 2, which removes an amide group from specific glutamine residues, might actually be critical to the peptides immunogenicity