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Fungal-targeted nanoconstructs (FTNx), using antisense oligonucleotides against FKS1 and CHS3 , can inhibit fungal cell wall synthesis genes, reduce fungal burden and improve survival in murine candidiasis models, exhibit broad-spectrum antifungal activity, including against clinical isolates of Candida auris ( Li et al., 2025a)

High ROS production in cancer cells requires high activity of cellular antioxidant systems, making cancer cells hypersensitive to agents that impair their antioxidant capacity

[DOI] [PubMed] [Google Scholar] 8.Dentico P, Volpe A, Buongiorno R, et al

Superoxide-free radicles and hydroxyl-free radicles act on lipid membranes and encourage the formation of lipid radicle and lipid peroxy radicles, which promote oxidative stress and cause lipid peroxidation