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Elevated calcium levels activate calpains and other calcium-dependent enzymes, which impair mitochondrial function and contribute to neuronal injury

Author contributions HH: Conceptualization, Methodology, Writingoriginal draft, Writingreview and editing

The compounds are synthesized and co-lyophilized under stringent analytical grade standards to ensure absolute sequence integrity and an ultra-high purity profile, preventing immunogenic cross-contamination during complex research protocols