Instead, they are just monitored by the FDA for adverse effects reported after the supplement is already available for purchase
A poorly dissolved reconstitution usually indicates either a problem with the BAC water (wrong type, contaminated) or a damaged lyocake from improper storage
However, these do have to be prescribed and administered by a healthcare professional, and are more likely to be given to people who have lifelong conditions affecting their ability to absorb B12 or who are at higher risk of consistent deficiency
1 Mecobalamin 50 mg or placebo was administered intramuscularly twice weekly for 16 weeks to 130 ALS patients who had suffered from ALS for less than one year, were classified as definite, probable, or probable-laboratory supported according to the Updated Awaji Criteria, had an ALS severity rating of grade 1 or 2, had a decrease of 1 or 2 points in the total score on the Revised ALS Functional Rating Scale-Revised (ALSFRS-R) 12 weeks prior to administration, and had a forced vital capacity (%FVC) of more than 60%
