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The most consistent pattern in Miami-area patients at Perfect B is that the first cycle establishes a baseline response, and the second cycle (after the 30-day rest) produces more visible outcomes

doi: 10.1016/j.ejmech.2024.116387 87

In addition, they may have other modes of action, as causing oxidative stress, genetic susceptibility, and epigenetic modifications (e.g., DNA methylation, miRNA) ( Specifically, some studies have demonstrated that EDCs such as bisphenol A (BPA), di-2-ethylhexyl phthalate (DEHP), dibutyl phthalate (DBP), and pesticides exert some of their endocrine-disrupting activity by influencing methylation patterns

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