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However, considering the large number of flavor ingredients available and the even greater number of possible combinations of mixtures in e-liquids (Zhu et al., 2014), the standard approach requires years of testing and thousands of laboratory animals

The Dutch government, for example, invited by the Philip Morris International tobacco company (PMI), subsequently promised to include its contribution in the report it was submitting to the committee

doi: 10.1111/j.1467-9655.2006.00364.x 84 RussellA.RahmanE

Many PAHs are recognized as human carcinogens and significantly contribute to the cancer risk associated with smoking