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The scar becomes covered with epithelium, and the damaged skin strengthens, making it increasingly resistant to mechanical damage

In individuals with certain genetic variants (HLA-DR), the immune system doesnt successfully clear the biotoxin signal, and inflammation continues even after exposures stopped

However, it has also been shown that sympathetic neurons undergo lipid peroxidation following cleavage of the p75 neurotrophic factor receptor, causing degeneration and cell death (121)

EMF-based strategies, such as combining ionizing radiation (IR) with ferroptosis inducers [74] or magnetic nanoparticle-guided iron delivery [12,75] , utilize electromagnetic bioeffects to selectively sensitize resistant PCa