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In a meta-analysis study conducted by Seth Kligerman and Charles White they noted that when comparing lunch cancer rates between men and women who smoke 40 packs a year women lung cancer rates were 27.9% (when compared to non-smokers) whereas men were only 9.6% (when compared to non-smokers)

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In a statement, Gottlieb suggested that the FDA would take a harder look at those flavors if they continued to pose a problem and said the agency is not restricting them, for now, because of their appeal to adults trying to quit tobacco

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