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However, when alveolar cell lines are treated with cigarette smoke condensate an increase in the hypomethylation of transcriptional enhancer markers located adjacent to cg05575921 was found, 86 suggesting that cg05575921 and other sites in AHRR may be actively involved in the induction of gene regulatory elements

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medical review by the Respiratory department, with input from the Adolescent Medicine department

However, genetic analyses showed that doubled carriers of the high smoking genotype had, on average, a 2.64-pound lower body weight