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By inhibiting NNMT, 5-Amino-1MQ has been observed in models to elevate NAD+, activate downstream metabolic regulators, and support pathways that encourage higher energy expenditure and reduced adiposity

A full blood count may reveal macrocytic anaemia (enlarged red blood cells) with elevated mean corpuscular volume (MCV), though this finding is not specific to B12 deficiency and can occur in liver disease independently

They reason that hydroxocobalamin is not a psychoactive substance or a synthetic chemical drug