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Moreover, rats chronically exposed to nicotine exhibited decreased pain thresholds and hyperalgesia following nicotine withdrawal [17, 18], suggesting the involvement of 7-type nAChRs (7-nAChRs) [19]

[10] By the end of the 20th century, anti-smoking campaigns in Germany were unable to exceed the effectiveness of the Nazi-era climax in the years 193941 and German tobacco health research was described by Robert N

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