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doi: 10.1093/cdn/nzaa066_020 [DOI] [Google Scholar] 224

PMID: 11253127 15

2.1 Features of cellular senescence The phenomenon of cellular senescence is a complex and multi-stage process, the course, and characteristics of which are often conditioned by numerous factors, such as the origin of the stress factor or the specificity of cells undergoing senescence [16, 17]

Yes, research in human muscle cell models shows that IGF-1 LR3 activates the Akt/mTOR pathway, increasing protein synthesis and myotube hypertrophy key markers of muscle growth and recovery