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That signal tells skin cells to turn on the production of collagen and elastin, while copper also acts as a helper to enzymes that stabilize new collagen, making it stronger. In one small clinical study, topical GHK-Cu use was associated with improved collagen production in approximately 70 percent of women over a 12-week period

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Seizure medications such as phenytoin and phenobarbital, as well as diabetes medications like metformin, can lower B12 levels over time