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The study was carried out through various computational methods using Autodock Vina for docking of the protein and ligand and Desmond for MD simulation

J Laparoendosc Adv Surg Tech A 30:369372 Aiolfi A, Cavalli M, Sozzi A, Lombardo F, Lanzaro A, Panizzo V, Bonitta G, Mendogni P, Bruni PG, Campanelli G, Bona D (2022) Medium-term safety and efficacy profile of paraesophageal hernia repair with Phasix-ST mesh: a single-institution experience

These effects generally subside within a few hours to a couple of days, depending on the laser type