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Zhao and colleagues developed an innovative two-stage nanoengineering strategy, using a gadoliniumeuropium metalorganic framework (GdEuMOF) loaded with tirapazamine (TPZ), designed to amplify TPZ activation through exacerbated hypoxia in breast tumors during microwave hyperthermia

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Genome-wide crispr screening identifies Dck and Ccnl1 as genes that contribute to gemcitabine resistance in pancreatic cancer