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Here are some overdose symptoms associated with each substance: Ritalin overdose symptoms: Restlessness Agitation Tremors or muscle twitching Increased heart rate and blood pressure Rapid breathing Elevated body temperature Dilated pupils Nausea and/or vomiting Confusion Seizures Loss of consciousness or coma Alcohol overdose symptoms: Confusion Vomiting Seizures Slow or irregular breathing Hypothermia (low body temperature) or hyperthermia (high body temperature) Bluish or pale skin, especially around the lips or fingertips Loss of consciousness or coma The effects of Ritalin and alcohol when taken together in excessive amounts may include a combination of the above, and the risks of respiratory depression, cardiovascular complications and even the possibility of death are heightened