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Self-prescribing high-dose B12 without medical indication is inadvisable, particularly for individuals with underlying health conditions

For patients with significant baseline B12 depletion or documented absorption issues, methylcobalamin (the natural form) or cyanocobalamin (the synthetic form) injectionstypically 1,000 mcg monthlyprovide more direct delivery and bypass the compromised absorption pathway

If it is cloudy, contains particles that will not dissolve, or looks discolored, do not use it