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Si se interrumpe el frmaco temporalmente, las lesiones se resuelven en 1 o 2 semanas

This has been demonstrated both in vitro studies using the THP-1 cell line treated with atorvastatin (0.120 M), as well as in randomized blind endpoint clinical studies in hypercholesterolemia patients using simvastatin (40 mg) or simvastatin/ezetimibe (10/10 mg) (Moutzouri et al., 2012

Pregnancy and lactation represent relative contraindications given absence of human safety data in these populations despite reassuring preclinical reproductive toxicology studies

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