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Indeed, in one hand, their activation is involved in neuroinflammation which endanger neurons via cytokines overproduction and on the other hand, atrophy and loss of activity leads to reduced neuronal protection ( 2+ oscillations than young ones under purinergic stimulation

Obesity is currently a growing public health concern (134) and as weight loss improves many obesity-related complications (135), there is a great deal of interest in developing weight-loss drugs

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