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we did not collect data on hormonal status, including menstrual cycle phase or oral contraceptive use, which may influence GSH levels given the known interactions between sex hormones and oxidative stress pathways

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An important role of GSSG in the NF activating signal cascade is suggested by the facts that the potent NF inducer, tetradecanoyl phorbol acetate, increases intracellular GSSG levels and GSSG/GSH ratios3