Advances in epigenetics link genetics to the environment and disease
Generally, chemical hepatotoxicity can be studied using six in vitro experimental systems, namely, isolated perfused liver preparations, liver slices, isolated hepatocytes in suspension, isolated hepatocytes culture and co-culture, cell lines and subcellular fractions [6,12,14,16,17]
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The HEK293T cells were maintained in culture medium comprised of DMEM supplemented with 10% fetal bovine serum and 1% streptomycin-penicillin
