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Purified CBD in psychiatric conditions (psychosis, schizophrenia and bipolar disorder) Many preclinical studies have demonstrated the role of pure CBD in ameliorating the symptoms of psychosis, and in models of schizophrenia (such as reducing stereotypy, hyperlocomotion, normalisation of social withdrawal and cognitive improvements) involving CB 1 and CB 2 , 5-HT1A receptor and neurogenesis factors [67,68,69]

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Until now many doctors have followed a self-medication hypothesis whereby patients smoke to counteract the stressful symptoms of schizophrenia or the side-effects of antipsychotic medication

2009: Lawsuits Sottera, the parent company of e-cigarette brand Smoking Everywhere filed suit in US Federal Court against the FDA