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While some studies indicate that caffeine may stimulate the production of glutathione in certain contexts, excessive caffeine consumption could lead to oxidative stress, which may counteract the benefits of glutathione

doi:10.1146/annurev.physiol.64.081501.131029

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Because serum alanine aminotransferase (ALT) levels have been reported to predict the histological course of NASH and because strict control of ALT is required to prevent the progression of NASH [13], the primary outcome of this study was a change in ALT levels