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Description

Biotransformation and quantitative determination of sulfur-containing metabolites of 1,4-dibromobutane in the rat

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Approximately 90% of the cases of ALS are classified as sporadic with no known etiology, while the remaining 10% appear to be familial, resulting in part from defects in copper/zinc superoxide dismutase 1 (SOD1), which leads to exaggerated oxidative stress and an unfolded protein response

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