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Interestingly, as for BRCA1, p62 expression is regulated by NRF2, due to the presence of ARE sequences in the p62 promoter, implying a positive-feedback loop [199]

Current Neuropharmacology, 18 (2), 108117

Plus, as an antioxidant, glutathione helps fight the oxidative stress that causes premature aging

Key considerationssuch as emerging clinical data, variability in product quality, and evolving regulatory oversighthighlight the importance of careful, evidence-based implementation