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In preclinical studies, compounds such as VX-765 and pralnacasan have demonstrated efficacy in inhibiting caspase-1 activation and protecting against inflammatory diseases

Safety Most studies on GHK-Cu are preclinical, so there is limited data on its safety in humans

Licensed 503A compounding pharmacies can now prepare both topical and injectable GHK-Cu under a physicians prescription, following the April 2026 reclassification that restored injectable GHK-Cu to Category 1 status

They can evaluate your specific condition, recommend appropriate dosages, and guide you on the best method of administration for addressing your IBS symptoms