Authors contributions IP: Writing of the manuscript, study design, data collection and interpretation, preparation of revisions
He has abstained from drinking alcohol for 1 year, he has completed primary addiction treatment, and he attends Alcoholics Anonymous meetings regularly
When interpreting the obtained research results, it was noted that, in some studies, the influence of the genotype concerning polymorphic variants of post-inflammatory cytokine genes on the risk/age of patients at the time of occurrence of neurodegenerative diseases depended on the ethnic group (for example, the influence of the IL1B -511TT genotype on the increased risk of Alzheimers disease (AD) in the Caucasian population [113]), or on the genetic background related, for example, to the apolipoprotein E ( APOE) genotype (for example, the TNF -308T allele was associated with an increased risk of AD among non-carriers of the APOE allele system 4, and the TNF -850T allele was associated with an increased risk of AD in APOE 4 carriers [114])
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