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Certaines conditions mdicales telles que les maladies rnales chroniques, la broncho-pneumopathie chronique obstructive, l'immunodpression aprs transplantation d'organe, l'obsit, les maladies cardiaques svres et la drpanocytose peuvent aussi conduire une carence en glutathion

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The NOX family precisely controls the spatiotemporal production of ROS through multi-layered mechanisms, including subunit assembly [123], phosphorylation [124], regulation of protein stability [125], and SUMOylation [126]

4.2.2 Other key signaling pathways NF-KB signaling lies at the nexus of many inflammatory cytokines and immune receptors, thus exerting bidirectional effects on ferroptosis