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Corticotropin-releasing factor-producing neurons in the rat activated by Interleukin-1

Important Medical Disclaimer: Many peptides discussed in this article are not FDA-approved for human use and are classified as research compounds

With the exception of acetylation, methylation and fatty acid conjugation, the strategy of phase II biotransformation is to convert a xenobiotic to a more hydrophilic form via the attachment of a chemical moiety which is ionizable at physiological pH