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Cardiovasc ResCo-inhibition of immunoproteasome subunits LMP2 and LMP7 enables prevention of transplant arteriosclerosis

Abstract Esculetin (ESC, 6,7-dihydroxycoumarin), a naturally occurring polyphenolic coumarin found in numerous medicinal and dietary plants, has emerged as a multi-target bioactive scaffold demonstrating anti-inflammatory, antioxidant, and antiproliferative properties in diverse preclinical models

Medical Review The scientific content on this page was reviewed for accuracy on 2026-07-19 By Dr

It has been investigated in laboratory settings for its role in peptide signaling and cellular response mechanisms