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Controlled elimination of intracellular H(2)O(2): regulation of peroxiredoxin, catalase, and glutathione peroxidase via post-translational modification

Lu, S.C., et al., Insulin and Glucocorticoid Dependence of Hepatic Gamma-Glutamylcysteine Synthetase and Glutathione Synthesis in the Rat Studies in Cultured-Hepatocytes and Invivo

The thyroid gland is just one of the glands in this system that includes the pituitary gland, the thymus, the adrenal glands, the pancreas, and many more

Additionally, GSH levels in tumor tissues decreased in the GGCT knockdown group but were restored by NAC, indicating that NAC could elevate the level of GSH by scavenging ROS (Fig