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Because of these roles, B12 is fundamental to: Red blood cell formation : Preventing macrocytic anemia and ensuring efficient oxygen transport Myelin synthesis : Maintaining the protective sheath around nerve fibers for rapid signal transmission DNA replication and repair : Supporting healthy cell division across all tissues, particularly the gastrointestinal lining and bone marrow Without adequate B12, you may experience fatigue, neurological symptoms, and hematologic problems that progressively worsen over time