IS: PGA 13 C 5 was obtained from MedChemExpress (Monmouth Junction, NJ, USA)
Here we also performed a Fisher r -to- Z transformation on the correlation coefficient and then tested for a difference in correlation strength between the age groups using a one-sided r.test in the psych package (Revelle, 2014)
Biomarkers tested Beyond behavioral testing, the researchers conducted extensive analysis of brain tissue, measuring various crucial markers: [1] Brain-derived neurotrophic factor (BDNF) Key neurotransmitters (acetylcholine, dopamine, GABA) Antioxidant markers (catalase, glutathione) Beta-amyloid levels Cyclic GMP This comprehensive approach allowed the research team to not only observe behavioral outcomes but also understand the underlying neurochemical changes driving these effects
Josipa Vlainic, Departments of Pharmacology and Pathology, Medical Faculty University of Zagreb, Zagreb 10000, Croatia