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Indeed, the clinical literature exhibits heterogeneity in design, dosing, duration, and outcome measures, frequent reliance on parent reported scales without uniform blinding, and underpowered samples that hinder strong inference and guideline development (Doherty et al., 2022

Characterized by an abnormal increase in the population of bacteria in the small intestine, SIBO contributes to digestive dysfunction, nutrient malabsorption, systemic inflammation, and chronic symptoms like bloating, diarrhea, and fatigue