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Parkinsons disease Huntingtons disease Dementia Gastroesophageal reflux disorder (GERD) ADHD Epilepsy Cerebral Palsy Down Syndrome Fibromyalgia Endocrine disorders (such as Addisons disease, Graves disease and Cushings syndrome) Night terrors and sleep disorders Autism Brain injury Depression Pinworm infection Allergies Obsessive-compulsive disorder (OCD) In some cases, certain prescription drugs may even cause or worsen bruxism, by stimulating neurotransmitters in the brain

A former industry lawyer now says that Liggett was pressured by other cigarette makers to abandon the effort because the "marketing and sale of a safe cigarette could result in infinite liability in civil litigation as it would constitute a direct or implied admission that all other cigarettes were unsafe." Liggett eventually abandoned the project

Research published in 2024 in Frontiers in Oral Health found that e-cigarette use is strongly associated with oral epithelial cell damage, dry mouth, inflammation, and disruption of the oral microbiome, all of which contribute to gum disease and dental decay