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Endogenous importance does not validate every product Water, glucose and insulin are also endogenous or physiologically essential, but their medical effects depend on dose, route, formulation, diagnosis and product quality

Bacher, A., Eberhardt, S., Fischer, M., Kis, K

J Hepatol 70:12221261

Acknowledgements This work was supported by the National Natural Science Foundation of China [grant numbers 82125037], Science Foundation for Distinguished Young Scholars of Jiangsu province [grant number BK20231528], Key R&D Program of Jiangsu Province [grant number BE2022815], Jiangsu Provincial Medical Innovation Center [grant number CXZX202225], Young Elite Scientists Sponsorship Program of the China Association for Science and Technology [grant number 2021-QNRC2-B17], and 333 high-level talents project of Jiangsu Province for Yang Yang [grant number BRA202202]