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A paradox: elevated 21-hydroxypregnenolone production in newborns with 21-hydroxylase deficiency

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Typical examples are flavonoids which are due to the number of hydroxyl groups very good in vitro antioxidants, however, under in vivo environment they undergo structural changes and transformations and therefore their antioxidant capacity is significantly reduced

The second phase of the study involved 'high excreters' of urinary metal ions being given a further 6 rounds of chelation if allocated to the topical glutathione arm or 6 rounds of placebo if previously allocated to the topical placebo arm of the study