Metabolomics and proteomics are valuable for analysing bacterial responses to environmental stress, including antibiotic treatment
[PubMed: 27797318] 17
Thus, in situ produced microbial folate may favourably influence the cellular nutrition of the local colonocytes and may be important in maintaining intestinal homeostasis and modulating gut microbiome function, e.g., through regulation of colon mucosal proliferation (i.e., colorectal cancer prevention) and its anti-inflammatory effects 248,249,256,257,277,278,279,280,281,282,283,284,285,286
That doesn't tell us what's happening in the liver, but I can tell you if it's high in the blood, the chances are it's gonna be high in the liver