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Each year, scholars at the Mackinac Center for Public Policy, a Michigan think tank, use a statistical analysis of available data to estimate smuggling rates for each state.[1] Their most recent report uses 2018 data and finds that smuggling rates generally rise in states after they adopt cigarette tax increases

The T21 law applies to sales of tobacco products including cigarettes, smokeless tobacco, hookah/waterpipe tobacco, cigars, pipe tobacco, liquid nicotine, electronic nicotine delivery systems including e-cigarettes and e-liquids to anyone under 21 years of age

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Thats with everything working optimally