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Astaxanthin: A super antioxidant from microalgae and its therapeutic potential

, Jauhiainen, S

In contrast, once the neural correlates of tolerance are established, opioid and non-opioid NOS inhibition likely compound, more easily surmounting enhanced NO synthesis associated with tolerance

Important limitations on this safety profile: the longest trial was 24 weeks, the total trial population is small by modern standards, and the clinical trials used oral dosing